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doi: 10.1007/s40291-021-00555-1
Irinotecan (220), methotrexate (221), cyclosporine A (222), and rifampicin (204) share similar UGT1A1 inhibitory activity in the treatment of cancer
GSH peroxidase 4 (GPX4) utilizes GSH to reduce lipid peroxides to innocuous lipid alcohols, thereby shielding cells from ferroptotic damage (Seibt et al
All procedures were designed to minimize animal suffering and were approved by the Institutional Animal Care and Use Committee
