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This activation leads to autophosphorylation of the subunits and subsequent phosphorylation of downstream signalling molecules, initiating a cascade of events that regulate various cellular processes such as glucose uptake and metabolism (Figure 3) [22]

GHRP-6 restored Akt phosphorylation by 80% in both control and DOX-treated muscle, but this effect was significantly reversed by AMD3100, implicating CXCR4 in Akt activation

doi: 10.1186/ar4429
Neurol Res (2010) 32(1):1015