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They can be water soluble or lipid soluble (ascorbate, glutathione, uric acid, etc., are water soluble, and tocopherols, ubiquinols, and carotenoids, etc., are lipid soluble)
Targeting amino acid metabolism Folic acid is a key regulator of nucleotide synthesis and methylation reactions
However, if your needs are higher due to diet or absorption issues, a standalone B12 supplement may be advised
Am J Hematol 93(9):1136-1141, 2018
