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Stem cell populations decrease
Using hepatocellular carcinoma (HCC) as a model, we investigated the effects of exogenous antioxidants N -acetylcysteine (NAC) and glutathione (GSH) on tumor formation and growth
Namely, redox-active metals, like Fe 2+ , react with peroxides generating highly active hydroxyl radicals (R-HO ) that further propagate the peroxidation reaction (43)
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