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Sci Total Environ 609:14331442 Guimares ATB, Estrela FN, de Lima Rodrigues AS, Chagas TQ, Pereira PS, Silva FG, Malafaia G (2021) Nanopolystyrene particles at environmentally relevant concentrations causes behavioral and biochemical changes in juvenile grass carp (Ctenopharyngodon idella)

NOX4 is highly expressed in neurons but it is activated by different mechanisms compared to NOX1 and NOX2 (Hordijk, 2006)
As a follow-up to Lehninger's work several years later, Nishikimi and co-workers observed that the gene that codes for gulonolactone oxidase is actually present in humans, but is not active due to the accumulation of several mutations that turned it into a non-functional pseudogene (Nishikimi & Yagi 1991)

The isoenzymes of the -class have a unique -loop at the C-terminus, while the isoenzymes of the -class contain an additional 19 amino acid sequence at the N-terminus
