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Such particular wide potential also occurred with glutamate disturbances [59,70] (i.e., counteracted ketamine-cognition dysfunction,-social withdrawal, and -anhedonia versus exerted additional anxiolytic effect in ketamine rats [59]

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Signs in infants and young children (often appearing around 4-6 months): Irritability and sleep disturbances Developmental delays or regression Poor muscle tone and coordination problems Speech difficulties White matter abnormalities on brain imaging In adults: Movement disorders Balance and coordination problems Cognitive decline and memory loss Mood changes The symptoms can range from mild behavioral changes to severe, progressive neurological deterioration

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