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Unlike tirzepatide (Mounjaro, Zepbound) it is a dual GIP/GLP-1 agonist that is FDA approved

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Rescue of mutant CBS activity has been documented by chemical chaperones 34,41 , haem arginate 42 , and proteostasis inhibitors 43 , suggesting a small molecule therapy could be developed 44,45
Furthermore, Treg-derived OBs enhance microglial repair activity via integrin receptors on microglial cells, thus improving white matter integrity and preserving neural function in the long term (80)
