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If they are, follow the instructions on the side of the pen to use it

Regarding intracellular roGFP2-based structure-function analysis of glutaredoxins, we now showed that the GSSG-dependent oxidation of the fused glutaredoxin moiety (and not the glutathionylation of the roGFP2 moiety) is rate-limiting unless saturating GSSG concentrations are present
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Understanding their role in these processes is essential for elucidating their contribution to health and disease and for developing strategies for therapeutic intervention
