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Description
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Common side effects include injection site reactions (pain, redness, swelling), gastrointestinal symptoms, and allergic reactions

Selective and membrane-permeable small-molecule inhibitors of NNMT reverse high-fat-diet-induced obesity in mice and remodel adipocyte metabolism (open-access)

Excessive NAM depletion directly reduces the substrate supply for NAD+ synthesis, leading to decreased intracellular NAD+ levels