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instead, they are actively released into the circulation, serving as systemic signals that can be read by distant tissues (Victorelli et al., 2023

Aitken RJ, Drevet JR, Moazamian A, Gharagozloo P Male infertility and oxidative stress: A focus on the underlying mechanisms

[DOI] [PMC free article] [PubMed] [Google Scholar] 57.Pillinger T., McCutcheon R.A., Vano L., Mizuno Y., Arumuham A., Hindley G., Beck K., Natesan S., Efthimiou O., Cipriani A., et al

This causes a rise in lipid peroxidation, which triggers the death of hair cells, supporting cells, stria vascularis cells, and SGNs (Rabio-Costa et al
