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Description
After analyzing 31 polymorphisms in 11 genes, it has been discovered that in presence of the C allele in SLC22A4 (OCTN1 rs1050152), and the two minor alleles (G) in SLC22A5 (OCTN2 rs2631367 and rs2631372) the time to progression was significantly improved ( General Features of OCTN1 (SLC22A4) and Implications in Cancer Organic cation transporter OCTN1 is another member of the SLC22 family

PLoS One 8: e66069, 2013

The less biosynthesis of carnitine resulted in the low transportation of fatty acids to the mitochondria for -oxidation

Biomedicine & Pharmacotherapy, 128 , 110352
