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In this model, the KD from one JAK2 molecule bound to a Box1Box2 motif from one receptor is inhibited by interacting with the PKD from a different JAK2 molecule bound to the opposing receptor within the receptor homodimer

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ARA-290 (cibinetide) for neuropathy: the clinical trial peptide If BPC-157 represents the strongest preclinical evidence for peptide-based nerve repair, ARA-290 represents the strongest clinical evidence