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Description
The p65 subunit of NF-B is the direct target of SIRT1, which, through deacetylation, can control the acetylation level of NF-B p65 to regulate the transcription level of the downstream genes, including those encoding IL-1, tumor necrosis factor (TNF-), IL-8, IL-6, and other inflammatory factors [27,28,29,30,31], thus regulating the inflammatory response
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Can FOXO4-DRI be felt working
They bind to specific receptors on the surface of cells, triggering a cascade of cellular responses
