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Part of EZH2 inhibitors is in clinical trials to verify the feasibility of combining with immune checkpoint inhibitors, such as tulmimetostat, XNW5004, CPI-1205 and SHR2554 (Table 2)

10.1038/s41579-024-01025-1 40 FaustmanD

Some factors make you more likely to have a vitamin B12 deficiency, such as aging, surgery to remove part of the stomach, Crohn's disease, celiac disease, and a vegan diet
The doctor will then closely monitor the patients blood work to ensure the body is safely clearing the medication before considering any dose increases
