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What is the KLOW cycle length
A number of researchers have reported that the activation of the SphK1/S1P signaling pathway marks the occurrence of autoimmune diseases, and the up-regulation of SphK1 is related to the pathogenesis of multiple sclerosis (Luo et al., 2017)

doi:10.1007/s00125-007-0793-y

For this reason, many practitioners suggest a cautious approach
