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It may provide anti-inflammatory and antioxidant effects

Most protocols dose by injection close to the site of injury (subcutaneous), though no human pharmacokinetic standard exists

While animal and in vitro studies have examined its activity, large-scale human clinical trials are limited, and its full safety and efficacy profile has not been established

Abstract Although most patients with relapsed/refractory B-cell acute lymphoblastic leukemia (B-ALL) receiving CD19-targeted chimeric antigen receptor (CAR) T cell therapy achieve remission, loss of CAR T cell functionality and subsequent relapse remains an unmet therapeutic need