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2 Materials and methods 2.1 Animal experiment and sampling The study was conducted at the experimental station of the Institute of Animal Nutrition, Friedrich-Loeffler-Institut (FLI), located in Braunschweig, Germany, in full compliance with the German Animal Welfare Act and approved by the Lower Saxony State Office for Consumer Protection and Food Safety (LAVES, Oldenburg, Germany) (AZ33.19-42502-04-16/2378)

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Selection criteria for genetic assessment of patients with familial melanoma

168 Liu et al demonstrated that exosomes released by TMAO-stimulated hepatocytes can promote HAEC apoptosis, inhibit cell migration, and endothelium-dependent vasodilation