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L-Carnitine attenuates cardiac dysfunction by ischemic insults through Akt signaling pathway

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Carnitine Synthesis and Dietary Uptake In animal tissues, L-carnitine concentrations are relatively high, typically between 0.2 and 6 mmol/kg with almost all in the heart and skeletal muscle, and it is synthesised de novo in animal cells by a multi-step process with N -trimethyl-lysine derived from protein degradation as the primary precursor and butyrobetaine as an intermediate

[DOI] [PMC free article] [PubMed] [Google Scholar] 105.Deng L., Zhou X., Lan Z., Tang K., Zhu X., Mo X., Zhao Z., Zhao Z., Wu M