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Thioredoxin-1 ameliorates myosin-induced autoimmune myocarditis by suppressing chemokine expressions and leukocyte chemotaxis in mice

For fluid retention, which may manifest as swelling in extremities, weight gain, or feeling of bloating, assessment of severity guides response

ENDO12 reduces inflammation but spares antiviral response CpG-ODN-initiated TLR9 signaling mediates the release of IL-6 and type I IFN-mediated response, which, if exacerbated, leads to systemic inflammation and contributes to autoimmunity but does not recapitulate a fully antiviral response, which involves both eTLR-dependent and independent mechanisms

Tang YQ, Yuan J, sapay G, sapay K, Tran D, Miller CJ, Ouellette AJ, Selsted ME: A cyclic antimicrobial peptide produced in primate leukocytes by the ligation of two truncated -defensins