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doi: 10.1080/10520295.2017.1421773

Darkening of the underarms-armpits after laser or waxing can occur due to several reasons: Friction and Irritation: Waxing involves pulling hair out from the root, which can lead to friction and irritation in the underarm area

In vivo experiments in mice with lung adenocarcinoma and mitogen-activated protein (MEK) and cyclin-dependent kinase 4/6 (CDK4/6) inhibition-induced senescence, the urokinase-type plasminogen activator receptor (uPAR)-directed CAR-T cells effectively depleted senescent tumor cells and prolonged survival