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Diagnostic innovation from a metabolic perspective In the realm of precision diagnostics, metabolism-associated technologies are increasingly enhancing the early detection and molecular stratification of CRC [135]

Recent studies have revealed that dysregulation of mitochondrial dynamicsincluding impaired mitophagy, imbalances in mitochondrial fusion and fission, and defects in mitochondrial biogenesisis closely associated with CRC initiation, progression, and resistance to therapy [46]

Phytotherapy Research, 27 (12), 1849-1853
