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Additionally, our transmission electron microscopy (TEM) observations align with this model: as lipid-soluble compounds, ARTs (e.g., DHA) can enter lipid droplets within the parasitic digestive vacuolea phenomenon consistent with prior studies [33]and disrupt the regular agregation of heme into hemozoin crystals

Arthritis Rheum 50:21912201

Published research uses varying doses depending on the model and endpoint

Lucentis improved on the results of Macugen
