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Its molecular mechanisms of action have been linked to the regulation of some critical genes, such as caspase-3, p53, and paraoxonase 1 (PON1), as well as signaling cascades, including the nuclear factor erythroid 2-related factor 2/heme oxygenase 1 (Nrf2/HO-1) pathway [34]

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Extending life span by increasing oxidative stress

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Sibbitt WL, Brandt JR, Johnson CR, Maldonado ME, Patel SR, Ford CC, et al .: The incidence and prevalence of neuropsychiatric syndromes in pediatric onset systemic lupus erythematosus

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Exposure to sunlight and other forms of UV radiation can damage the DNA in skin cells, causing genetic mutations that can lead to the development of cancerous cells

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