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doi: 10.1159/000212963
At the cellular level, vitamin B12 is involved in DNA synthesis and neuroprotection, acting as a cofactor for enzymes critical to these processes, such as methionine synthase and methylmalonyl-CoA mutase (, )
Stress & substances: Manage stress and limit alcohol and smoking, which can accelerate cellular aging
If tests show deficiency, replacement is justified and often rapidly helpful
