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10.1523/JNEUROSCI.1749-20.2020 [DOI] [PMC free article] [PubMed] [Google Scholar] Jiang N, Kolhekar AS, Jacobs PS, Mains RE, Eipper BA, & Taghert PH (2000)

doi: 10.1016/s0300-483x(00)00281-x
It activates the SIRT1/peroxisome proliferator-activated receptor-gamma coactivator 1 (PGC-1) pathway to promote mitochondrial biogenesis, regulate mitochondrial homeostasis, and inhibit the high mobility group protein (HMGB)1/TLR4/p38/extracellular regulated protein kinases (ERK)1/2 pathway to reduce inflammatory responses in CIA mice (259)

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