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Additionally, metformins influence on nitric oxide (NO) production, poly (ADP-ribose) polymerase 1 (PARP-1) inhibition, and modulation of reactive oxygen species (ROS) and sulfur species further contributes to its multifaceted actions

However, research suggests that prebiotics and probiotics may help restore microbial balance and enhance the guts ability to metabolize and neutralize mold-related toxins before they trigger further disruption

10.1161/01.RES.84.3.253 97 KlevayL

Another relevant mouse model is the experimental autoimmune encephalomyelitis (EAE) model, in which demyelination is mediated by the immune system (Constantinescu et al., 2011