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doi: 10.1016/j.ecoenv.2024.115995 50 MaQAugustoDGMontero-MartinGCaillierSJOsoegawaKCreeBACet al

This analgesic self-synergy is significantly attenuated by the administration of naloxone, an opioid receptor antagonist, at the spinal level (Raffa et al., 2000)

There are experimental data in mice that the antidepressant effects of NAC are blocked by AMPA antagonists [140], suggesting the involvement of AMPA receptors in the antidepressant-like effects of NAC
