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Acknowledgements Work in the authors laboratory is funded by grants from Stiftelsen KG Jebsen (project SKGJ- MED-017), the University of Oslo World-leading research program on human immunology (WL-IMMUNOLOGY), the Research Council of Norway (projects 333380, 324302, 295844, 287234) and the South-Eastern Norway Regional Health Authority (projects 2016113, 2018068, 2020027 and 2023075)

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