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PMID: 57 YoshidaMMinagawaSArayaJSakamotoTHaraHTsubouchiKet al

mtDNA mutations are implicated in various disorders, including mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes (MELAS), maternally inherited Leigh syndrome (MILS), myoclonic epilepsy with ragged red fibers (MERRF), Lebers hereditary optic neuropathy (LHON), Kearns-Sayre syndrome, Pearson syndrome, and chronic progressive external ophthalmoplegia (CPEO)

Safety, tolerability and efficacy of the glutaminyl cyclase inhibitor PQ912 in Alzheimers disease: results of a randomized, double-blind, placebo-controlled phase 2a study

Selective alanine transporter utilization creates a targetable metabolic niche in pancreatic cancer