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It is worth noting that TMAO can also significantly increase the level of ROS in DCs through the mitochondrial dysfunction pathway

Fecal excretion of total carnitine was less than 1% of the administered dose.10 After attainment of steady state following 4 days of oral administration of levocarnitine tablets (1980 mg q12h) or oral solution (2000 mg q12h) to 15 healthy male volunteers, the mean urinary excretion of levocarnitine during a single dosing interval (12h) was about 9% of the orally administered dose (uncorrected for endogenous urinary excretion)

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10.1042/cs1030339 Clin Sci