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The theoretical justification for antibody treatment of CDAD is based on this observation that a person with only a mild case of CDAD possesses high levels of anti-toxin A IgG serum titers, while patients with severe case of CDAD have shown low levels of anti-TcdA Ig titers, specifically IgM, IgG2 and IgG3 isotypes [161163]

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We evaluated key features of ferroptosis in newly developed molecular dynamics models of lipid membranes to investigate the biophysical consequences of lipid peroxidation, and generated hypotheses about how lipid peroxides contribute to cell death during ferroptosis

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