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COVID-19 patients treated with NAC were older, predominantly male, and with more comorbidities such as hypertension, dyslipidemia, diabetes, and COPD when compared with those not on NAC (all p 56 years), smoking, overweight/obesity and those people with previous health conditions (for example, cardiovascular disease, respiratory or diabetes), who are particularly susceptible and are therefore more likely to experience severe or critical COVID-19

PMID 30231877