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The oxidative state of the ER was measured by incorporation of PEG-maleimide (mm(PEG) 24 ) (ThermoFisher) as described (Tyra et al., 2012)
doi: 10.1113/JP271539 208

The ability of cells to generate Se metabolites more rapid oxidation of glutathione and other thiols within tumor cells, resulting in the production of ROS and peroxides

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