Glutathione IV Therapy: Benefits & Uses
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Description
Introduction Glutathione (GSH), -L-glutamyl-L-cysteinylglycine, is an important cellular reducing agent, which prevents damage to cellular components caused by free radicals or peroxides
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However, in the presence of LRRK2 mutations, the LRRK2 kinase activity is increased, leading to up-regulated TH expression and increased DA synthesis [44]
Among them, the small molecule, NXP800, was initially develop to target the activity of the transcription factor Heat Shock Factor 1 (HSF1), which is the major regulator of the HSR [6, 7]
