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A novel aspect introduced in this review is the acknowledgment of the spatiotemporal heterogeneity of ROS, emphasizing their capacity to play distinct roles at various stages of disease progression, cellular fates, and on different target molecules, organelles, and cells

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What the Preclinical Data Shows A 2025 systematic review in HSS Journal by Vasireddi, Hahamyan, Salata, and colleagues at Case Western Reserve University identified 36 studies published between 1993 and 2024