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While berberine is safe for most people to use, there are some possible side effects, like abdominal discomfort, constipation, diarrhea and nausea

Evangelista E, Lopez R, Barateau L, et al

Disponible en: Xie, J., y otros (2014)
In 3 trials of 169 people, those who consumed multivitamins with guarana had an increased benefit of mood and cognitive performance and reduced mental fatigue compared to those who consumed the vitamins alone
