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Advances in Gerontology, 26 (1), 20-37

Alzheimer's therapeutics targeting amyloid beta 1-42 oligomers II: Sigma-2/PGRMC1 receptors mediate Abeta 42 oligomer binding and synaptotoxicity

17 The degradation of the proteoglycan aggregates and generation of a large quantity of non-aggregating proteoglycans is thought to be a precursor to disc degeneration

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