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Another significant metformin side effect: vitamin B12 deficiency

Normal saline (0.9% sodium chloride) Normal saline is occasionally used for peptide reconstitution, but it offers no preservative benefit and can slightly alter the peptide environment compared to bacteriostatic water

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The severity of symptoms does not always correlate with serum B12 levels, and some patients with borderline-low results may experience significant neurological impairment
