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Description
As an endogenous ligand for G protein-coupled receptor 81 (GPR81), lactate reaches adipose tissue and binds to GPR81 on the adipocyte surface, reducing lipolysis and thus free fatty acid (FFA) release by inhibiting the cAMP/PKA pathway (Zhi et al., 2024)

GHRP-6 guide: Benefits, dosage, side effects, and best stacks (2025)

Functional enrichment, GSEA, and IPA analysis were performed on the results as described for RNA-seq analysis above

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