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doi: 10.3389/fendo.2023.1139874

Hassanein EHM, Kamel EO, Ali FEM, Ahmed MAR (2021) Berberine and/or zinc protect against methotrexate-induced intestinal damage: role of GSK-3/NRF2 and JAK1/STAT-3 signaling pathways

Dark circles have two primary causes that are frequently conflated but require different active responses: vascular pooling in the blood vessels around the eye, which produces a bluish-purple discolouration most visible through thin skin in that area, and surface pigmentation from UV exposure, post-inflammatory marks, or accumulated melanin, which produces a brownish discolouration

Uric acid and glut athione levels during short-term whole body cold exposure