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MTHFR mutation also can increase environmental risks for psychiatric disorders, such as MDD through interaction between genetic and epigenetic factors

Tregs mediate immunosuppression by expressing FOXP3 to downregulate NFAT/NF-B signaling, thereby inhibiting effector cytokines (e.g., IL-2) and immune responses [34]

Single-cell RNA-seq ties macrophage polarization to growth rate of intracellular salmonella
