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Description
A distinct sequence (ATAAA)n separates methylated and unmethylated domains at the 5-end of the GSTP1 CpG island
The importance of this finding is highlighted by the fact that GWAS utilizes a less biased approach by first detecting, among a large pool of candidate SNPs, those SNPs that strongly correlate with disease risk or progression
One of the constraints of nose-to-brain administration of medicines is the speed with which pharmaceuticals are cleared by the nasal mucociliary clearance system
Finally, pharmacological targeting of the activity of -glutamyltransferases prevents the breakdown of circulating GSH, reduces tumour cysteine levels and slows tumour growth
