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Synergetic Activation of P38 Mitogen-Activated Protein Kinase and Caspase-3-Like Proteases for Execution of Calyculin a-Induced Apoptosis but Not N-Methyl-D-Aspartate-Induced Necrosis in Mouse Cortical Neurons

3 I-M, inhibition of C10:2 with etomoxir significantly downregulated the expression of pyroptosis proteins NLRP3, caspase1, IL-18 and IL-1, while these pyroptosis makers were restored by osthole, and there is no difference between the effect of osthole and etomoxir on C10:2 concentration

Biochem J [Internet], 472 (2015), pp