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Description
Both treatments lowered anti-dsDNA antibodies, with chlorogenic acid also decreasing pro-inflammatory cytokines (IL-17 A and IL-17 F), suggesting benefits for lupus management
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In the advancement of treatment strategies, although approaches like mitochondria-targeted antioxidants (e.g., MitoQ) and macrophage metabolic reprogramming (e.g., SDH inhibitors) have shown significant efficacy in animal models, their clinical translation faces severe challenges in targeted delivery and microenvironment adaptation
