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Q5: Do I still need sun protection

The expression of the VD metabolism genes CYP2R1 and CYP27A1 (25-hydroxylase), CYP27B1 (1--hydroxylase), and vitamin D receptor (VDR) were downregulated in the livers of mice fed an HFD (GSH- deficient) compared with control diet-fed group

Firstly, we observed that metformin was able to partially alleviate OA pain in the monosodium iodoacetate (MIA)-induced mouse model as assessed by animal behavior tests

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