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Absence of Cochleotoxicity Measured by Standard and High-Frequency Pure Tone Audiometry in a Trial of Once- versus Three-Times-Daily Tobramycin in Cystic Fibrosis Patients
49 HaraguchiM.TsujimotoH.FukushimaM.HiguchiI.KuribayashiH.UtsumiH.et al (2002)
Specifically, copper's ability to enhance MMP expression, particularly MMP-1, which regulates collagen breakdown, might lead to a temporary increase in cellular debris or a transient inflammatory response as the skin purges and rebuilds
