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ANDREW HUBERMAN: So its like, its an abnormal growth

EDITING BY Bailee Stark, MD AND Arthur Broadstock, MD FAWM Dr

(AAOS Orthopaedic Sports Medicine) screened 544 peer-reviewed articles and identified 36 qualifying studies: 35 preclinical (rodent and dog models) and exactly 1 human trial

Drug Interactions None specific to proline However, metabolic interactions can occur due to: Corticosteroids: Increased protein catabolism altered AA requirements Insulin therapy: Affects amino-acid uptake and protein synthesis Acidbase modifying agents: Can alter amino-acid metabolism indirectly Nutritional/PN Interactions Vitamin C deficiency: Impairs proline hydroxyproline conversion, compromising collagen