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Clinical advantages and disadvantages of anabolic bone therapies targeting the WNT pathway

Hypoxia-inducible factor 1 (HIF-1) promotes the expression of ferritin light chain (FTL), thereby enhancing iron storage and boosting resistance to ferroptosis
10.1016/j.neuro.2013.04.006 243 SugumarM.SevananM.SekarS

Here, the sGAG act as a molecular glue leading to recognition modes in which sGAG interact with two VEGF 165 -HBDs
