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Thirdly, the functional groups of the substrate molecule must be compatible with the reaction conditions

10.1002/mus.24647 65 CoyneP

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Moreover, compounds associated with nucleotide metabolism, such as 5-methylthioadenosine, xanthine, and hypoxanthine, were also elevated, alongside phenylalanine metabolism intermediates like phenylacetaldehyde and folate metabolism-related substances including 4-aminobenzoic acid
