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It also plays a key role in the synthesis of vitamins, including vitamins K and B12 (153)
Background :Azoxymethane (AOM) is a potent carcinogenic agent commonly used to induce colon cancer in rats and mice, with the cytotoxicity of AOM mediated by oxidative stress
Once inside the cell, endogenous enzymes readily convert glutathione reduced ethyl ester into reduced glutathione (Levy et al, 1993)
